2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0497A
    Niclosamide sodium
    		Inhibitor
    Niclosamide (BAY2353) sodium is an orally active antihelminthic agent used in parasitic infection research. Niclosamide sodium is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide sodium has biological activities against cancer, and inhibits DNA replication in Vero E6 cells.
    Niclosamide sodium
  • HY-B0433B
    Quinine hemisulfate
    		Inhibitor
    Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine hemisulfate
  • HY-B1198S
    Piperonyl butoxide-d9
    		Inhibitor
    Piperonyl butoxide-d9 is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice.
    Piperonyl butoxide-d<sub>9</sub>
  • HY-B1118S
    Secnidazole-d6
    		Inhibitor
    Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research[1].
    Secnidazole-d<sub>6</sub>
  • HY-107483S
    Cambendazole-d7
    Cambendazole-d7 is the deuterium labeled Cambendazole[1].
    Cambendazole-d<sub>7</sub>
  • HY-136440S
    Hydroxymetronidazole-d4
    		Inhibitor
    Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
    Hydroxymetronidazole-d<sub>4</sub>
  • HY-135811S
    Desethyl chloroquine-d4
    		Inhibitor
    Desethyl chloroquine-d4 is the deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity[1][2].
    Desethyl chloroquine-d<sub>4</sub>
  • HY-N0176S
    Dihydroartemisinin-d3
    		Inhibitor
    Dihydroartemisinin-d3 is the deuterium labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent.
    Dihydroartemisinin-d<sub>3</sub>
  • HY-18719ES
    Endoxifen-d5
    		Inhibitor
    Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study[1][2].
    Endoxifen-d<sub>5</sub>
  • HY-B0806AS
    Proguanil-d4 hydrochloride
    		Inhibitor
    Proguanil-d4 (hydrochloride) is the deuterium labeled Proguanil hydrochloride. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor[1][2].
    Proguanil-d<sub>4</sub> hydrochloride
  • HY-B0223S2
    Albendazole-d7
    		Inhibitor
    Albendazole-d7 is the deuterium labeled Albendazole. Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. Albendazole is used for the research gastrointestinal parasites in humans and animals[1][2].
    Albendazole-d<sub>7</sub>
  • HY-13832S2
    Atovaquone-d5
    		Inhibitor
    Atovaquone-d5 is the deuterium labeled Atovaquone. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia[1][2].
    Atovaquone-d<sub>5</sub>
  • HY-B0094S
    Artemisinin-d3
    		Activator
    Artemisinin-d3 is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
    Artemisinin-d<sub>3</sub>
  • HY-B1322R
    Amodiaquine dihydrochloride dihydrate (Standard)
    		Inhibitor
    Amodiaquine (dihydrochloride dihydrate) (Standard) is the analytical standard of Amodiaquine (dihydrochloride dihydrate). This product is intended for research and analytical applications. Amodiaquine dihydrochloride dihydrate (Amodiaquin dihydrochloride dihydrate), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine dihydrochloride dihydrate is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
    Amodiaquine dihydrochloride dihydrate (Standard)
  • HY-N0176A
    α-Dihydroartemisinin
    		Inhibitor
    α-Dihydroartemisinin is a natural product that can be found in artemisinin. α-Dihydroartemisinin also shows antimalarial activity.
    α-Dihydroartemisinin
  • HY-155087
    Anticancer agent 140
    		Inhibitor
    Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities.
    Anticancer agent 140
  • HY-N2381R
    Menthone (Standard)
    		Inhibitor
    Menthone (Standard) is the analytical standard of Menthone. This product is intended for research and analytical applications. Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis.
    Menthone (Standard)
  • HY-156082
    RyRs activator 3
    		Inhibitor
    RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity.
    RyRs activator 3
  • HY-N10255
    Trypacidin
    Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process.
    Trypacidin
  • HY-A0148
    Halofantrine
    		Inhibitor
    Halofantrine (SKF-102886 free base) is a highly lipophilic antimalarial active against Chloroquine-resistant strains of Plasmodium falciparum. Halofantrine blocks HERG potassium channels.
    Halofantrine
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.