2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1160
    Bitoscanate
    		Inhibitor ≥98.0%
    Bitoscanate (p-Phenylene diisothiocyanate) is an organic chemical compound used in the treatment of hookworms.
    Bitoscanate
  • HY-113752
    MMV019313
    		Inhibitor 99.54%
    MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 µM. MMV019313 has activity against P. falciparum (Parasite).
    MMV019313
  • HY-N1482S1
    Methyl palmitate-d31
    		99.11%
    Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].
    Methyl palmitate-d<sub>31</sub>
  • HY-N1480R
    (-)-Fucose (Standard)
    		Inhibitor
    (-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth.
    (-)-Fucose (Standard)
  • HY-N8707
    Homobutein
    		Inhibitor 98.35%
    Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation.
    Homobutein
  • HY-W006672
    Dibenzo[b,e]oxepin-11(6H)-one
    		Inhibitor
    Dibenzo[b,e]oxepin-11(6H)-one (Compound 1a) is a dibenzoxepinone derivative that exhibits significant antiparasitic activity.
    Dibenzo[b,e]oxepin-11(6H)-one
  • HY-B1073
    Morantel tartrate
    		Inhibitor 99.01%
    Morantel tartrate is a broad spectrum anthelmintic, effective and low toxicity.
    Morantel tartrate
  • HY-B1088
    Clopidol
    		Inhibitor 99.77%
    Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts.
    Clopidol
  • HY-B0497B
    Niclosamide monohydrate
    		Inhibitor
    Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research. Niclosamide monohydrate is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells.
    Niclosamide monohydrate
  • HY-164052
    Antiparasitic agent-23
    		Inhibitor 98.77%
    Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism.
    Antiparasitic agent-23
  • HY-17470R
    Mizoribine (Standard)
    Mizoribine (Standard) is the analytical standard of Mizoribine. This product is intended for research and analytical applications. Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively.
    Mizoribine (Standard)
  • HY-121657
    Ornidazole diol
    		Inhibitor 99.24%
    Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
    Ornidazole diol
  • HY-116724
    Robenidine
    		Inhibitor
    Robenidine is a coccidiostat agent that can be used for the research of coccidiosis caused by parasites in the Eimeria genus.
    Robenidine
  • HY-120924
    BRD9185
    BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model.
    BRD9185
  • HY-B1370A
    (S)-Hydroxychloroquine
    		Inhibitor
    (S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine. Hydroxychloroquine, a synthetic antimalarial agent, inhibits Toll-like receptor 7/9 (TLR7/9) signaling, and shows efficiently inhibits SARS-CoV-2 infection in vitro.
    (S)-Hydroxychloroquine
  • HY-B1331R
    Cyromazine (Standard)
    Cyromazine (Standard) is the analytical standard of Cyromazine. This product is intended for research and analytical applications. Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats.
    Cyromazine (Standard)
  • HY-111543
    AN11251
    		Inhibitor
    AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines.
    AN11251
  • HY-B0221S
    Amphotericin B-13C6
    Amphotericin B-13C6 is 13C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    Amphotericin B-<sup>13</sup>C<sub>6</sub>
  • HY-139854
    DNDI-6148
    DNDI-6148 is a novel preclinical candidate for the research of visceral leishmaniasis.
    DNDI-6148
  • HY-10572BR
    (Rac)-Efavirenz (Standard)
    (Rac)-Efavirenz (Standard) is the analytical standard of (Rac)-Efavirenz. This product is intended for research and analytical applications. (Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
    (Rac)-Efavirenz (Standard)
Parasite Isoform Comparison

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